Current Analysis on

Guest Editor 

Haiyun Liu, Ph.D.

Institute for Advanced Interdisciplinary Research, University of Jinan

Manuscript submission deadline: 15th March, 2018

Point of care (POC) testing including point-of-care devices, methods, strategies, achievements, challenges and trends

A Brief Description of the Aims and Objectives

The advent of fluorescent labeling technologies plus the plethora of sophisticated light microscope techniques now available make studying dynamic processes in living cells almost commonplace. Especially, STED, STOM, SPR, SERS are applied insingle cell imaginganalysis, single molecule analysisand 3D cell cultures.

Point of care (POC) testing, which is defined as near patient testing in a hospital, doctor’s office, clinic, or home, offers advantages when a rapid answer is required, or when suitable facilities or logistics chains are unavailable. Wearable chemosensorsand paper-based microfluidic analysis divicesare current research hot topic.

In addition, biomarkers are on the verge of becoming powerful diagnostic tools for various human diseases. Detection of CTCs, as a liquid biopsyof tumors, can be used for early diagnosis of cancers, earlier evaluation of cancer recurrence and chemotherapeutic efficacy, and choice of individual sensitive anti-cancer drugs. The most diseases originate from the deficiency or malfunctioning of endogenous genes inside the body.Gene therapy and genetic mtutation analysis, whose primary goal is to treat diseases at the fundamental (genetic) level, is expected to impact a broad range of healthcare issues ranging from genetically inherited or acquired diseases, to cancer. With concurrent advancements in imaging modalities involving nanoparticles, concepts such as multimodality, combination therapies, theranostics and image guided therapies emerged. Nanotherapiesalso show promise in complementing traditional therapeutic avenues, such as surgery, chemotherapy, and radiation therapy. 

Potential titles for proposed manuscripts publications but are not limited to the following:

  • Portable point-of-care diagnostic devices
  • Advances in point-of-care diagnostic devices in cancers
  • Novel biochip platform for nucleic acid analysis
  • Current technologies and recent developments for point-of-care testing
  • Point-of-care diagnostic tools to detect CTC as biomarkers of disease
  • Point-of-care nucleic acid detection using nanotechnology
  • Recent advances in nucleic acid detection
  • Trends in lab-on-chip interferometric biosensors for point-of-care diagnostics
  • Point of care testing: recent achievements and challenges
  • Wearable chemo sensors and paper-based microfluidic analysis: recent advances and future challenges

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